Showing metabocard for Chlorine (BMDB0000492)
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| Version | 1.0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Creation Date | 2016-09-30 22:31:32 UTC | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Update Date | 2020-06-04 22:50:13 UTC | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| BMDB ID | BMDB0000492 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Secondary Accession Numbers |
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| Metabolite Identification | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Common Name | Chlorine | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description | Chloride ion, also known as chloride(1-) or Cl, belongs to the class of inorganic compounds known as homogeneous halogens. These are inorganic non-metallic compounds in which the largest atom is a nobel gas. Chloride ion exists as a solid, possibly soluble (in water), and an extremely strong acidic compound (based on its pKa) molecule. Chloride ion exists in all living species, ranging from bacteria to humans. In cattle, chloride ion is involved in the metabolic pathway called the kidney function pathway. Chloride ion is a potentially toxic compound. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Structure |  | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Synonyms |
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| Chemical Formula | Cl | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Average Molecular Weight | 35.453 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Monoisotopic Molecular Weight | 34.968852707 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IUPAC Name | chloride | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Traditional Name | chloride | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| CAS Registry Number | 16887-00-6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| SMILES | [Cl-] | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| InChI Identifier | InChI=1S/ClH/h1H/p-1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| InChI Key | VEXZGXHMUGYJMC-UHFFFAOYSA-M | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Chemical Taxonomy | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description | belongs to the class of inorganic compounds known as homogeneous halogens. These are inorganic non-metallic compounds in which the largest atom is a nobel gas. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kingdom | Inorganic compounds | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Super Class | Homogeneous non-metal compounds | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Class | Homogeneous halogens | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sub Class | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Direct Parent | Homogeneous halogens | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Alternative Parents | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Substituents |
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| Molecular Framework | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| External Descriptors |
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| Ontology | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Status | Detected and Quantified | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Origin | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Biofunction | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Application | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cellular locations |
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| Physical Properties | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| State | Gas | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Experimental Properties |
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| Predicted Properties |
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| Spectra | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Spectra |
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| Biological Properties | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cellular Locations |
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| Biospecimen Locations |
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| Pathways |
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| Normal Concentrations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Abnormal Concentrations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| External Links | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| HMDB ID | HMDB0000492 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DrugBank ID | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Phenol Explorer Compound ID | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| FooDB ID | FDB006557 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| KNApSAcK ID | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Chemspider ID | 4514529 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| KEGG Compound ID | C00698 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| BioCyc ID | CL- | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| BiGG ID | 50130 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Wikipedia Link | Chloride | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| METLIN ID | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| PubChem Compound | 312 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| PDB ID | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| ChEBI ID | 17996 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| References | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Synthesis Reference | Weber, Rainer; Bulan, Andreas; Haas, Michel; Warsitz, Rafael; Werner, Knud. Production of chlorine from hydrogen chloride and oxygen. PCT Int. Appl. (2007), 30pp. CODEN: PIXXD2 WO 2007134861 A1 20071129 CAN 148:35931 AN 2007:1361621 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Material Safety Data Sheet (MSDS) | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| General References |
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Enzymes
- General function:
- Defense mechanisms
- Specific function:
- Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. Modulates the activity of the epithelial sodium channel (ENaC) complex, in part by regulating the cell surface expression of the ENaC complex. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the transporter SLC4A7. Can inhibit the chloride channel activity of ANO1 (By similarity). Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity).
- Gene Name:
- CFTR
- Uniprot ID:
- P35071
- Molecular weight:
- 167758.0
- General function:
- Involved in carboxypeptidase activity
- Specific function:
- Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity).
- Gene Name:
- ACE
- Uniprot ID:
- P12820
- Molecular weight:
- 10681.0
- General function:
- Involved in carboxypeptidase activity
- Specific function:
- Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator (By similarity). Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage of angiotensin II, may be an important regulator of heart function (By similarity). By cleavage of angiotensin II, may also have a protective role in acute lung injury (By similarity). Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity (By similarity).
- Gene Name:
- ACE2
- Uniprot ID:
- Q58DD0
- Molecular weight:
- 93067.0
- General function:
- Inorganic ion transport and metabolism
- Specific function:
- Not Available
- Gene Name:
- SLC26A6
- Uniprot ID:
- Q08DQ8
- Molecular weight:
- 83332.0
- General function:
- Involved in collagen binding
- Specific function:
- Not Available
- Gene Name:
- TN-X
- Uniprot ID:
- O18977
- Molecular weight:
- 447384.0
- General function:
- Involved in chloride ion binding
- Specific function:
- Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function (By similarity).
- Gene Name:
- CTSC
- Uniprot ID:
- Q3ZCJ8
- Molecular weight:
- 51949.0
- General function:
- Involved in chloride channel activity
- Specific function:
- Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:2548852). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity). The alpha1/beta2/gamma2 receptor and the alpha2/beta2/gamma2 receptor exhibit synaptogenic activity (By similarity). Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).
- Gene Name:
- GABRB2
- Uniprot ID:
- P0C2W5
- Molecular weight:
- 54451.0
- General function:
- Involved in chloride channel activity
- Specific function:
- GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone (By similarity).
- Gene Name:
- GABRP
- Uniprot ID:
- Q5EA06
- Molecular weight:
- 50430.0
- General function:
- Inorganic ion transport and metabolism
- Specific function:
- Not Available
- Gene Name:
- clcn5
- Uniprot ID:
- Q68V31
- Molecular weight:
- 20749.0
- General function:
- Involved in voltage-gated chloride channel activity
- Specific function:
- Not Available
- Gene Name:
- clc2
- Uniprot ID:
- Q6A194
- Molecular weight:
- 15399.0
- General function:
- Posttranslational modification, protein turnover, chaperones
- Specific function:
- Can insert into membranes and form chloride ion channels.
- Gene Name:
- CLIC4
- Uniprot ID:
- Q9XSA7
- Molecular weight:
- 28727.0
- General function:
- Not Available
- Specific function:
- Not Available
- Gene Name:
- CLCA4
- Uniprot ID:
- Q3SYU0
- Molecular weight:
- 103420.0
- General function:
- Involved in voltage-gated chloride channel activity
- Specific function:
- Not Available
- Gene Name:
- CLIC3
- Uniprot ID:
- A6QL90
- Molecular weight:
- 26628.0
- General function:
- Involved in voltage-gated chloride channel activity
- Specific function:
- Not Available
- Gene Name:
- CLIC2
- Uniprot ID:
- A2VE46
- Molecular weight:
- 28336.0
- General function:
- Involved in extracellular ligand-gated ion channel acti
- Specific function:
- Not Available
- Gene Name:
- GABRG1
- Uniprot ID:
- A6QQP6
- Molecular weight:
- 53800.0
- General function:
- Inorganic ion transport and metabolism
- Specific function:
- Not Available
- Gene Name:
- CLCN2
- Uniprot ID:
- A6QNR5
- Molecular weight:
- 99214.0
- General function:
- Involved in calcium channel activity
- Specific function:
- May be involved in mediating calcium-activated chloride conductance (PubMed:8537359). May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC.
- Gene Name:
- Not Available
- Uniprot ID:
- P54281
- Molecular weight:
- 100306.0
- General function:
- Involved in UDP-activated nucleotide receptor activity
- Specific function:
- Not Available
- Gene Name:
- Not Available
- Uniprot ID:
- Q6QHU8
- Molecular weight:
- 17510.0
- General function:
- Involved in chloride ion binding
- Specific function:
- Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and beta-alanine. Channel characteristics depend on the subunit composition; heteropentameric channels are activated by lower glycine levels and display faster desensitization (By similarity). Plays an important role in the down-regulation of neuronal excitability (PubMed:11178872). Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol (By similarity). Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol (By similarity).
- Gene Name:
- GLRA1
- Uniprot ID:
- P57695
- Molecular weight:
- 52614.0
- General function:
- Involved in potassium:chloride symporter activity
- Specific function:
- Not Available
- Gene Name:
- SLC12A5
- Uniprot ID:
- A8KC65
- Molecular weight:
- 129418.0
- General function:
- Inorganic ion transport and metabolism
- Specific function:
- Not Available
- Gene Name:
- CLCN7
- Uniprot ID:
- A6QQR2
- Molecular weight:
- 88807.0
- General function:
- Inorganic ion transport and metabolism
- Specific function:
- Not Available
- Gene Name:
- CLCN4
- Uniprot ID:
- Q4F894
- Molecular weight:
- 84893.0
- General function:
- Involved in chloride channel activity
- Specific function:
- Ligand-gated chloride channel subunit which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. May be involved in GABA-A receptor assembly, and GABA-A receptor immobilization and accumulation by gephyrin at the synapse.
- Gene Name:
- GABRA5
- Uniprot ID:
- Q08E50
- Molecular weight:
- 52172.0
- General function:
- Involved in chloride channel activity
- Specific function:
- Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine (By similarity). Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
- Gene Name:
- GABRB1
- Uniprot ID:
- P08220
- Molecular weight:
- 54130.0
- General function:
- Involved in protein binding
- Specific function:
- Not Available
- Gene Name:
- Not Available
- Uniprot ID:
- Q4QRP1
- Molecular weight:
- 15737.0
- General function:
- Inorganic ion transport and metabolism
- Specific function:
- Slowly voltage-gated channel mediating the exchange of chloride ions against protons (By similarity). Functions as antiporter and contributes to the acidification of the lysosome lumen and may be involved in maintaining lysosomal pH (By similarity). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (By similarity). The presence of conserved gating glutamate residues is typical for family members that function as antiporters (By similarity).
- Gene Name:
- CLCN7
- Uniprot ID:
- Q4PKH3
- Molecular weight:
- 88831.0
- General function:
- Involved in chloride ion binding
- Specific function:
- Required for normal hearing. It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti. Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion. Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture. Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens.
- Gene Name:
- CLIC5
- Uniprot ID:
- P35526
- Molecular weight:
- 48959.0
- General function:
- Involved in chloride channel activity
- Specific function:
- GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
- Gene Name:
- GABRA4
- Uniprot ID:
- P20237
- Molecular weight:
- 61547.0
- General function:
- Involved in chloride channel activity
- Specific function:
- Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity). The alpha1/beta2/gamma2 receptor, alpha2/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity whereas the alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity (By similarity). Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).
- Gene Name:
- GABRG2
- Uniprot ID:
- P22300
- Molecular weight:
- 55265.0
- General function:
- Involved in GABA-A receptor activity
- Specific function:
- Not Available
- Gene Name:
- Not Available
- Uniprot ID:
- A0JN66
- Molecular weight:
- 4036.0
- General function:
- Involved in extracellular ligand-gated ion channel acti
- Specific function:
- Not Available
- Gene Name:
- GABRA3
- Uniprot ID:
- Q0II82
- Molecular weight:
- 31434.0
- General function:
- Posttranslational modification, protein turnover, chaperones
- Specific function:
- Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions (By similarity).
- Gene Name:
- CLIC1
- Uniprot ID:
- Q5E9B7
- Molecular weight:
- 26992.0
- General function:
- Involved in cation:chloride symporter activity
- Specific function:
- Not Available
- Gene Name:
- Not Available
- Uniprot ID:
- O18978
- Molecular weight:
- 130394.0
- General function:
- Not Available
- Specific function:
- Not Available
- Gene Name:
- Not Available
- Uniprot ID:
- O97740
- Molecular weight:
- 17189.0
- General function:
- Involved in chloride channel activity
- Specific function:
- GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
- Gene Name:
- GABRA3
- Uniprot ID:
- P10064
- Molecular weight:
- 55284.0
- General function:
- Involved in chloride channel activity
- Specific function:
- Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:2842688). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity). The alpha2/beta2/gamma2 receptor exhibits synaptogenic activity whereas the alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity (By similarity).
- Gene Name:
- GABRA2
- Uniprot ID:
- P10063
- Molecular weight:
- 51146.0
- General function:
- Not Available
- Specific function:
- Seems to act as a chloride ion channel (By similarity). Plays a role in retina development (By similarity).
- Gene Name:
- CLCC1
- Uniprot ID:
- Q1LZF8
- Molecular weight:
- 61812.0
- General function:
- Involved in chloride ion binding
- Specific function:
- Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents.
- Gene Name:
- GLRB
- Uniprot ID:
- Q9GJS9
- Molecular weight:
- 56039.0
- General function:
- Involved in chloride channel activity
- Specific function:
- Probable chloride channel. May be involved in cell adhesion (By similarity).
- Gene Name:
- TTYH1
- Uniprot ID:
- Q2KJ98
- Molecular weight:
- 49230.0
- General function:
- Involved in extracellular ligand-gated ion channel acti
- Specific function:
- GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission (By similarity).
- Gene Name:
- GABRR2
- Uniprot ID:
- Q0II76
- Molecular weight:
- 54122.0
- General function:
- Involved in chloride channel activity
- Specific function:
- Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity (By similarity).
- Gene Name:
- ANO4
- Uniprot ID:
- A6QLE6
- Molecular weight:
- 107708.0
- General function:
- Involved in chloride channel activity
- Specific function:
- Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:3037384). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity). The alpha1/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity (By similarity). GABRA1-mediated plasticity in the orbitofrontal cortex regulates context-dependent action selection (By similarity). Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).
- Gene Name:
- GABRA1
- Uniprot ID:
- P08219
- Molecular weight:
- 51856.0
- General function:
- Involved in chloride channel activity
- Specific function:
- Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell (PubMed:12657675). Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (By similarity). Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone (By similarity).
- Gene Name:
- FXYD1
- Uniprot ID:
- Q3SZX0
- Molecular weight:
- 10447.0
- General function:
- Involved in cell volume homeostasis
- Specific function:
- Not Available
- Gene Name:
- CLNS1A
- Uniprot ID:
- Q1LZ90
- Molecular weight:
- 26207.0