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Record Information
Version1.0
Creation Date2016-09-30 22:49:16 UTC
Update Date2020-05-21 16:29:08 UTC
BMDB IDBMDB0001967
Secondary Accession Numbers
  • BMDB01967
Metabolite Identification
Common NameCarbon dioxide
DescriptionCarbon dioxide, also known as [CO2] or e 290, belongs to the class of inorganic compounds known as other non-metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of 'other non-metals'. Carbon dioxide is possibly neutral. Carbon dioxide exists in all living species, ranging from bacteria to humans. Carbon dioxide is a potentially toxic compound.
Structure
Thumb
Synonyms
ValueSource
[CO2]ChEBI
Carbonic anhydrideChEBI
CO2ChEBI
e 290ChEBI
e-290ChEBI
e290ChEBI
R-744ChEBI
Carbon oxideHMDB
Carbon-12 dioxideHMDB
Carbonic acid anhydrideHMDB
Carbonic acid gasHMDB
Anhydride, carbonicHMDB
Dioxide, carbonHMDB
Chemical FormulaCO2
Average Molecular Weight44.0095
Monoisotopic Molecular Weight43.989829244
IUPAC Namemethanedione
Traditional Namecarbon dioxide
CAS Registry Number124-38-9
SMILES
O=C=O
InChI Identifier
InChI=1S/CO2/c2-1-3
InChI KeyCURLTUGMZLYLDI-UHFFFAOYSA-N
Chemical Taxonomy
Description belongs to the class of inorganic compounds known as other non-metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of 'other non-metals'.
KingdomInorganic compounds
Super ClassHomogeneous non-metal compounds
ClassOther non-metal organides
Sub ClassOther non-metal oxides
Direct ParentOther non-metal oxides
Alternative Parents
Substituents
  • Other non-metal oxide
  • Inorganic oxide
Molecular FrameworkNot Available
External Descriptors
Ontology
StatusExpected but not Quantified
Origin
  • Endogenous
  • Exogenous
BiofunctionNot Available
ApplicationNot Available
Cellular locations
  • Cytoplasm
  • Endoplasmic reticulum
  • Golgi
  • Mitochondria
  • Nucleus
  • Peroxisome
Physical Properties
StateLiquid
Experimental Properties
PropertyValueReference
Melting Point-56.5 °CNot Available
Boiling PointNot AvailableNot Available
Water Solubility1.48 mg/mL at 25 °CNot Available
LogP0.83HANSCH,C ET AL. (1995)
Predicted Properties
PropertyValueSource
logP-0.63ALOGPS
logP-0.28ChemAxon
logS0.63ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area34.14 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity6.38 m³·mol⁻¹ChemAxon
Polarizability2.57 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash Key
GC-MSGC-MS Spectrum - EI-B (Non-derivatized)splash10-0006-9000000000-ffb540455919d1e43969View in MoNA
GC-MSGC-MS Spectrum - EI-B (Non-derivatized)splash10-0006-9000000000-ffb540455919d1e43969View in MoNA
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positivesplash10-0006-9000000000-9afc44eaa1fe34c4f458View in MoNA
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, PositiveNot AvailableView in JSpectraViewer
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, PositiveNot AvailableView in JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0006-9000000000-eb2207f7400e9144fff7View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0006-9000000000-eb2207f7400e9144fff7View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0006-9000000000-eb2207f7400e9144fff7View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0006-9000000000-b7e6c1e22f1f90c5a8e0View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0006-9000000000-b7e6c1e22f1f90c5a8e0View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0006-9000000000-b7e6c1e22f1f90c5a8e0View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0006-9000000000-a1e091bb1f5fa6e9cbc7View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0006-9000000000-a1e091bb1f5fa6e9cbc7View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0006-9000000000-a1e091bb1f5fa6e9cbc7View in MoNA
MSMass Spectrum (Electron Ionization)splash10-0006-9000000000-e1cf88df1066f206d01fView in MoNA
Biological Properties
Cellular Locations
  • Cytoplasm
  • Endoplasmic reticulum
  • Golgi
  • Mitochondria
  • Nucleus
  • Peroxisome
Biospecimen Locations
  • Kidney
  • Liver
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
KidneyExpected but not QuantifiedNot QuantifiedNot SpecifiedNot SpecifiedNormal
  • Not Applicable
details
LiverExpected but not QuantifiedNot QuantifiedNot SpecifiedNot SpecifiedNormal
  • Not Applicable
details
Abnormal Concentrations
Not Available
HMDB IDHMDB0001967
DrugBank IDDB09157
Phenol Explorer Compound IDNot Available
FooDB IDFDB014084
KNApSAcK IDNot Available
Chemspider ID274
KEGG Compound IDC00011
BioCyc IDCARBON-DIOXIDE
BiGG ID33506
Wikipedia LinkCarbon_dioxide
METLIN ID3199
PubChem Compound280
PDB IDNot Available
ChEBI ID16526
References
Synthesis ReferenceCallahan, Richard A. Process and apparatus for producing liquid carbon dioxide. U.S. (1993), Patent US5233837 (https://patents.google.com/patent/US5233837)
Material Safety Data Sheet (MSDS)Not Available
General ReferencesNot Available

Enzymes

General function:
Coenzyme transport and metabolism
Specific function:
Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference (By similarity). Required for adipocyte cell viability and metabolic homeostasis (By similarity).
Gene Name:
SPTLC1
Uniprot ID:
Q3MHG1
Molecular weight:
52788.0
Reactions
Palmityl-CoA + L-Serine → 3-Dehydrosphinganine + Carbon dioxidedetails
General function:
Lipid transport and metabolism
Specific function:
Performs the first committed step in the biosynthesis of isoprenes.
Gene Name:
MVD
Uniprot ID:
Q0P570
Molecular weight:
43732.0
Reactions
Adenosine triphosphate + 5-Diphosphomevalonic acid → ADP + Hydrogen phosphate + Isopentenyl pyrophosphate + Carbon dioxidedetails
General function:
Lipid transport and metabolism
Specific function:
Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor (By similarity).
Gene Name:
GCDH
Uniprot ID:
Q2KHZ9
Molecular weight:
48472.0
Reactions
Glutaryl-CoA → Crotonoyl-CoA + Carbon dioxidedetails
Glutaryl-CoA + electron-transfer flavoprotein → Crotonoyl-CoA + Reduced electron-transfer flavoprotein + Carbon dioxidedetails
General function:
Energy production and conversion
Specific function:
Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
Gene Name:
ALDH6A1
Uniprot ID:
Q07536
Molecular weight:
58063.0
Reactions
Malonic semialdehyde + Coenzyme A + NAD → Acetyl-CoA + Carbon dioxide + NADHdetails
General function:
Coenzyme transport and metabolism
Specific function:
Not Available
Gene Name:
GCAT
Uniprot ID:
Q0P5L8
Molecular weight:
45166.0
Reactions
Palmityl-CoA + L-Serine → 3-Dehydrosphinganine + Carbon dioxidedetails
General function:
Involved in adenosylmethionine decarboxylase activity
Specific function:
Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
Gene Name:
AMD1
Uniprot ID:
P50243
Molecular weight:
38365.0
Reactions
S-Adenosylmethionine → S-Adenosylmethioninamine + Carbon dioxidedetails
General function:
Cell wall/membrane/envelope biogenesis
Specific function:
Not Available
Gene Name:
TGDS
Uniprot ID:
A6QLW2
Molecular weight:
40666.0
Reactions
Uridine diphosphate glucuronic acid → UDP-D-Xylose + Carbon dioxidedetails
General function:
Energy production and conversion
Specific function:
May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency.
Gene Name:
IDH1
Uniprot ID:
Q9XSG3
Molecular weight:
46785.0
Reactions
Isocitric acid + NADP → Oxoglutaric acid + NADPH + Carbon dioxidedetails
General function:
Amino acid transport and metabolism
Specific function:
Catalyzes the biosynthesis of histamine from histidine.
Gene Name:
HDC
Uniprot ID:
Q5EA83
Molecular weight:
73912.0
Reactions
L-Histidine → Histamine + Carbon dioxidedetails
General function:
Energy production and conversion
Specific function:
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal. May have a broader specificity and oxidize other aldehydes in vivo.
Gene Name:
ALDH1A1
Uniprot ID:
P48644
Molecular weight:
54806.0
Reactions
N10-Formyl-THF + NADP + Water → Tetrahydrofolic acid + Carbon dioxide + NADPHdetails
General function:
Energy production and conversion
Specific function:
Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate.
Gene Name:
PCK1
Uniprot ID:
Q8HYZ4
Molecular weight:
69353.0
Reactions
Guanosine triphosphate + Oxalacetic acid → Guanosine diphosphate + Phosphoenolpyruvic acid + Carbon dioxidedetails
General function:
Secondary metabolites biosynthesis, transport and catabolism
Specific function:
Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).
Gene Name:
TMLHE
Uniprot ID:
Q0VC74
Molecular weight:
49837.0
Reactions
N6,N6,N6-Trimethyl-L-lysine + Oxoglutaric acid + Oxygen → 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine + Succinic acid + Carbon dioxidedetails
3-Dehydroxycarnitine + Oxoglutaric acid + Oxygen → L-Carnitine + Succinic acid + Carbon dioxidedetails
General function:
Coenzyme transport and metabolism
Specific function:
Not Available
Gene Name:
ALAS1
Uniprot ID:
A6QLI6
Molecular weight:
71062.0
Reactions
Glycine + Succinyl-CoA → 5-Aminolevulinic acid + Carbon dioxidedetails
General function:
Energy production and conversion
Specific function:
Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex (By similarity). The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (By similarity). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (By similarity).
Gene Name:
DLST
Uniprot ID:
P11179
Molecular weight:
48973.0
Reactions
Oxoadipic acid + Coenzyme A → Glutaryl-CoA + Carbon dioxidedetails
General function:
Coenzyme transport and metabolism
Specific function:
Involved in the catabolism of quinolinic acid (QA).
Gene Name:
QPRT
Uniprot ID:
Q3T063
Molecular weight:
31151.0
Reactions
Nicotinic acid mononucleotide + Pyrophosphate + Carbon dioxide → Quinolinic acid + Phosphoribosyl pyrophosphatedetails
General function:
Energy production and conversion
Specific function:
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
Gene Name:
BCKDHA
Uniprot ID:
P11178
Molecular weight:
51678.0
Reactions
Ketoleucine + Thiamine pyrophosphate → 3-Methyl-1-hydroxybutyl-ThPP + Carbon dioxidedetails
Alpha-ketoisovaleric acid + Thiamine pyrophosphate → 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxidedetails
3-Methyl-2-oxovaleric acid + Thiamine pyrophosphate → 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxidedetails
General function:
Energy production and conversion
Specific function:
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
Gene Name:
BCKDHB
Uniprot ID:
P21839
Molecular weight:
42935.0
Reactions
Ketoleucine + Thiamine pyrophosphate → 3-Methyl-1-hydroxybutyl-ThPP + Carbon dioxidedetails
Alpha-ketoisovaleric acid + Thiamine pyrophosphate → 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxidedetails
3-Methyl-2-oxovaleric acid + Thiamine pyrophosphate → 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxidedetails
General function:
Involved in aminocarboxymuconate-semialdehyde decarboxy
Specific function:
Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway (By similarity).
Gene Name:
ACMSD
Uniprot ID:
Q0II68
Molecular weight:
37923.0
Reactions
2-Amino-3-carboxymuconic acid semialdehyde → 2-Aminomuconic acid semialdehyde + Carbon dioxidedetails
General function:
Amino acid transport and metabolism
Specific function:
Key enzyme in the degradation of tyrosine.
Gene Name:
HPD
Uniprot ID:
Q5EA20
Molecular weight:
44963.0
Reactions
4-Hydroxyphenylpyruvic acid + Oxygen → Homogentisic acid + Carbon dioxidedetails
General function:
Involved in iron ion binding
Specific function:
Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
Gene Name:
PHYH
Uniprot ID:
O18778
Molecular weight:
38770.0
Reactions
Phytanoyl-CoA + Oxoglutaric acid + Oxygen → 2-Hydroxyphytanoyl-CoA + Succinic acid + Carbon dioxidedetails
General function:
Involved in iron ion binding
Specific function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Gene Name:
P4HA3
Uniprot ID:
Q75UG4
Molecular weight:
61023.0
Reactions
L-Proline + Oxoglutaric acid + Oxygen → Hydroxyproline + Succinic acid + Carbon dioxidedetails
General function:
Energy production and conversion
Specific function:
Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.
Gene Name:
PDHX
Uniprot ID:
P22439
Molecular weight:
53886.0
Reactions
Pyruvic acid + Coenzyme A + NAD → Acetyl-CoA + Carbon dioxide + NADHdetails
General function:
Amino acid transport and metabolism
Specific function:
Catalyzes the production of GABA.
Gene Name:
GAD1
Uniprot ID:
Q0VCA1
Molecular weight:
66784.0
Reactions
L-Aspartic acid → Beta-Alanine + Carbon dioxidedetails
L-Glutamic acid → Gamma-Aminobutyric acid + Carbon dioxidedetails
3-Sulfinoalanine → Hypotaurine + Carbon dioxidedetails
Cysteic acid → Taurine + Carbon dioxidedetails
General function:
Amino acid transport and metabolism
Specific function:
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
Gene Name:
ODC1
Uniprot ID:
P27117
Molecular weight:
51346.0
Reactions
Ornithine → Putrescine + Carbon dioxidedetails
General function:
Amino acid transport and metabolism
Specific function:
Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
Gene Name:
DDC
Uniprot ID:
P27718
Molecular weight:
54294.0
Reactions
L-Tyrosine → Tyramine + Carbon dioxidedetails
5-Hydroxykynurenine → 5-Hydroxykynurenamine + Carbon dioxidedetails
L-Tryptophan → Tryptamine + Carbon dioxidedetails
General function:
Cell wall/membrane/envelope biogenesis
Specific function:
Involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis.
Gene Name:
NSDHL
Uniprot ID:
Q3ZBE9
Molecular weight:
39902.0
Reactions
4a-Methylzymosterol-4-carboxylic acid + NADP → 3-Keto-4-methylzymosterol + NADPH + Carbon dioxidedetails
General function:
Energy production and conversion
Specific function:
2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.
Gene Name:
OGDH
Uniprot ID:
Q148N0
Molecular weight:
115808.0
Reactions
Oxoadipic acid + Coenzyme A → Glutaryl-CoA + Carbon dioxidedetails
General function:
Energy production and conversion
Specific function:
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene Name:
PDHA1
Uniprot ID:
A7MB35
Molecular weight:
43388.0
Reactions
Pyruvic acid + Coenzyme A + NAD → Acetyl-CoA + Carbon dioxide + NADHdetails
Pyruvic acid + Lipoamide → S-Acetyldihydrolipoamide-E + Carbon dioxidedetails
General function:
Energy production and conversion
Specific function:
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene Name:
PDHB
Uniprot ID:
P11966
Molecular weight:
39126.0
Reactions
Pyruvic acid + Coenzyme A + NAD → Acetyl-CoA + Carbon dioxide + NADHdetails
Pyruvic acid + Lipoamide → S-Acetyldihydrolipoamide-E + Carbon dioxidedetails
General function:
Amino acid transport and metabolism
Specific function:
Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is L-aspartate. Does not exhibit any decarboxylation activity toward glutamate.
Gene Name:
GADL1
Uniprot ID:
A6QM00
Molecular weight:
59380.0
Reactions
3-Sulfinoalanine → Hypotaurine + Carbon dioxidedetails
Cysteic acid → Taurine + Carbon dioxidedetails
General function:
Energy production and conversion
Specific function:
Not Available
Gene Name:
ME1
Uniprot ID:
B8YB77
Molecular weight:
63372.0
Reactions
NADP + L-Malic acid → NADPH + Hydrogen + Carbon dioxide + Pyruvic aciddetails
General function:
Not Available
Specific function:
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
Gene Name:
PISD
Uniprot ID:
Q58DH2
Molecular weight:
47244.0
Reactions
an L-1-Phosphatidylserine → Carbon dioxide + an L-1-Phosphatidylethanolaminedetails
PS(14:0/14:0) → PE(14:0/14:0) + Carbon dioxidedetails
PS(14:0/14:1(9Z)) → PE(14:0/14:1(9Z)) + Carbon dioxidedetails
PS(14:0/16:0) → PE(14:0/16:0) + Carbon dioxidedetails
PS(14:0/16:1(9Z)) → PE(14:0/16:1(9Z)) + Carbon dioxidedetails
PS(14:0/18:0) → PE(14:0/18:0) + Carbon dioxidedetails
PS(14:0/18:1(9Z)) → PE(14:0/18:1(9Z)) + Carbon dioxidedetails
PS(14:0/18:2(9Z,12Z)) → PE(14:0/18:2(9Z,12Z)) + Carbon dioxidedetails
PS(14:0/18:3(9Z,12Z,15Z)) → PE(14:0/18:3(9Z,12Z,15Z)) + Carbon dioxidedetails
PS(14:0/20:3(8Z,11Z,14Z)) → PE(14:0/20:3(8Z,11Z,14Z)) + Carbon dioxidedetails
PS(14:0/20:4(5Z,8Z,11Z,14Z)) → PE(14:0/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxidedetails
PS(14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
PS(14:1(9Z)/14:1(9Z)) → PE(14:1(9Z)/14:1(9Z)) + Carbon dioxidedetails
PS(14:1(9Z)/16:0) → PE(14:1(9Z)/16:0) + Carbon dioxidedetails
PS(14:1(9Z)/16:1(9Z)) → PE(14:1(9Z)/16:1(9Z)) + Carbon dioxidedetails
PS(14:1(9Z)/18:0) → PE(14:1(9Z)/18:0) + Carbon dioxidedetails
PS(14:1(9Z)/18:1(9Z)) → PE(14:1(9Z)/18:1(9Z)) + Carbon dioxidedetails
PS(14:1(9Z)/18:2(9Z,12Z)) → PE(14:1(9Z)/18:2(9Z,12Z)) + Carbon dioxidedetails
PS(14:1(9Z)/18:3(9Z,12Z,15Z)) → PE(14:1(9Z)/18:3(9Z,12Z,15Z)) + Carbon dioxidedetails
PS(14:1(9Z)/20:3(8Z,11Z,14Z)) → PE(14:1(9Z)/20:3(8Z,11Z,14Z)) + Carbon dioxidedetails
PS(14:1(9Z)/20:4(5Z,8Z,11Z,14Z)) → PE(14:1(9Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxidedetails
PS(14:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(14:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
PS(16:0/16:1(9Z)) → PE(16:0/16:1(9Z)) + Carbon dioxidedetails
PS(16:0/18:0) → PE(16:0/18:0) + Carbon dioxidedetails
PS(16:0/18:1(11Z)) → PE(16:0/18:1(11Z)) + Carbon dioxidedetails
PS(16:0/18:1(9Z)) → PE(16:0/18:1(9Z)) + Carbon dioxidedetails
PS(16:0/18:2(9Z,12Z)) → PE(16:0/18:2(9Z,12Z)) + Carbon dioxidedetails
PS(16:0/18:3(6Z,9Z,12Z)) → PE(16:0/18:3(6Z,9Z,12Z)) + Carbon dioxidedetails
PS(16:0/18:3(9Z,12Z,15Z)) → PE(16:0/18:3(9Z,12Z,15Z)) + Carbon dioxidedetails
PS(16:0/20:0) → PE(16:0/20:0) + Carbon dioxidedetails
PS(16:0/20:1(11Z)) → PE(16:0/20:1(11Z)) + Carbon dioxidedetails
PS(16:0/20:3(8Z,11Z,14Z)) → PE(16:0/20:3(8Z,11Z,14Z)) + Carbon dioxidedetails
PS(16:0/20:4(5Z,8Z,11Z,14Z)) → PE(16:0/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxidedetails
PS(16:0/22:0) → PE(16:0/22:0) + Carbon dioxidedetails
PS(16:0/22:1(13Z)) → PE(16:0/22:1(13Z)) + Carbon dioxidedetails
PS(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
PS(16:1(9Z)/16:1(9Z)) → PE(16:1(9Z)/16:1(9Z)) + Carbon dioxidedetails
PS(16:1(9Z)/18:0) → PE(16:1(9Z)/18:0) + Carbon dioxidedetails
PS(16:1(9Z)/18:1(9Z)) → PE(16:1(9Z)/18:1(9Z)) + Carbon dioxidedetails
PS(16:1(9Z)/18:2(9Z,12Z)) → PE(16:1(9Z)/18:2(9Z,12Z)) + Carbon dioxidedetails
PS(16:1(9Z)/18:3(9Z,12Z,15Z)) → PE(16:1(9Z)/18:3(9Z,12Z,15Z)) + Carbon dioxidedetails
PS(16:1(9Z)/20:3(8Z,11Z,14Z)) → PE(16:1(9Z)/20:3(8Z,11Z,14Z)) + Carbon dioxidedetails
PS(16:1(9Z)/20:4(5Z,8Z,11Z,14Z)) → PE(16:1(9Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxidedetails
PS(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
PS(18:0/18:0) → PE(18:0/18:0) + Carbon dioxidedetails
PS(18:0/18:1(11Z)) → PE(18:0/18:1(11Z)) + Carbon dioxidedetails
PS(18:0/18:1(9Z)) → PE(18:0/18:1(9Z)) + Carbon dioxidedetails
PS(18:0/18:2(9Z,12Z)) → PE(18:0/18:2(9Z,12Z)) + Carbon dioxidedetails
PS(18:0/18:3(6Z,9Z,12Z)) → PE(18:0/18:3(6Z,9Z,12Z)) + Carbon dioxidedetails
PS(18:0/18:3(9Z,12Z,15Z)) → PE(18:0/18:3(9Z,12Z,15Z)) + Carbon dioxidedetails
PS(18:0/20:0) → PE(18:0/20:0) + Carbon dioxidedetails
PS(18:0/20:1(11Z)) → PE(18:0/20:1(11Z)) + Carbon dioxidedetails
PS(18:0/20:3(8Z,11Z,14Z)) → PE(18:0/20:3(8Z,11Z,14Z)) + Carbon dioxidedetails
PS(18:0/20:4(5Z,8Z,11Z,14Z)) → PE(18:0/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxidedetails
PS(18:0/20:4(8Z,11Z,14Z,17Z)) → PE(18:0/20:4(8Z,11Z,14Z,17Z)) + Carbon dioxidedetails
PS(18:0/22:0) → PE(18:0/22:0) + Carbon dioxidedetails
PS(18:0/22:1(13Z)) → PE(18:0/22:1(13Z)) + Carbon dioxidedetails
PS(18:0/22:5(7Z,10Z,13Z,16Z,19Z)) → PE(18:0/22:5(7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
PS(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
PS(18:1(11Z)/18:1(11Z)) → PE(18:1(11Z)/18:1(11Z)) + Carbon dioxidedetails
PS(18:1(11Z)/18:2(9Z,12Z)) → PE(18:1(11Z)/18:2(9Z,12Z)) + Carbon dioxidedetails
PS(18:1(11Z)/18:3(6Z,9Z,12Z)) → PE(18:1(11Z)/18:3(6Z,9Z,12Z)) + Carbon dioxidedetails
PS(18:1(11Z)/18:3(9Z,12Z,15Z)) → PE(18:1(11Z)/18:3(9Z,12Z,15Z)) + Carbon dioxidedetails
PS(18:1(11Z)/20:0) → PE(18:1(11Z)/20:0) + Carbon dioxidedetails
PS(18:1(11Z)/20:1(11Z)) → PE(18:1(11Z)/20:1(11Z)) + Carbon dioxidedetails
PS(18:1(11Z)/22:0) → PE(18:1(11Z)/22:0) + Carbon dioxidedetails
PS(18:1(11Z)/22:1(13Z)) → PE(18:1(11Z)/22:1(13Z)) + Carbon dioxidedetails
PS(18:1(9Z)/18:1(9Z)) → PE(18:1(9Z)/18:1(9Z)) + Carbon dioxidedetails
PS(18:1(9Z)/18:2(9Z,12Z)) → PE(18:1(9Z)/18:2(9Z,12Z)) + Carbon dioxidedetails
PS(18:1(9Z)/18:3(6Z,9Z,12Z)) → PE(18:1(9Z)/18:3(6Z,9Z,12Z)) + Carbon dioxidedetails
PS(18:1(9Z)/18:3(9Z,12Z,15Z)) → PE(18:1(9Z)/18:3(9Z,12Z,15Z)) + Carbon dioxidedetails
PS(18:1(9Z)/20:0) → PE(18:1(9Z)/20:0) + Carbon dioxidedetails
PS(18:1(9Z)/20:1(11Z)) → PE(18:1(9Z)/20:1(11Z)) + Carbon dioxidedetails
PS(18:1(9Z)/20:3(8Z,11Z,14Z)) → PE(18:1(9Z)/20:3(8Z,11Z,14Z)) + Carbon dioxidedetails
PS(18:1(9Z)/20:4(5Z,8Z,11Z,14Z)) → PE(18:1(9Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxidedetails
PS(18:1(9Z)/22:0) → PE(18:1(9Z)/22:0) + Carbon dioxidedetails
PS(18:1(9Z)/22:1(13Z)) → PE(18:1(9Z)/22:1(13Z)) + Carbon dioxidedetails
PS(18:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(18:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
PS(18:2(9Z,12Z)/18:2(9Z,12Z)) → PE(18:2(9Z,12Z)/18:2(9Z,12Z)) + Carbon dioxidedetails
PS(18:2(9Z,12Z)/18:3(6Z,9Z,12Z)) → PE(18:2(9Z,12Z)/18:3(6Z,9Z,12Z)) + Carbon dioxidedetails
PS(18:2(9Z,12Z)/18:3(9Z,12Z,15Z)) → PE(18:2(9Z,12Z)/18:3(9Z,12Z,15Z)) + Carbon dioxidedetails
PS(18:2(9Z,12Z)/20:0) → PE(18:2(9Z,12Z)/20:0) + Carbon dioxidedetails
PS(18:2(9Z,12Z)/20:1(11Z)) → PE(18:2(9Z,12Z)/20:1(11Z)) + Carbon dioxidedetails
PS(18:2(9Z,12Z)/20:3(8Z,11Z,14Z)) → PE(18:2(9Z,12Z)/20:3(8Z,11Z,14Z)) + Carbon dioxidedetails
PS(18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z)) → PE(18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxidedetails
PS(18:2(9Z,12Z)/22:0) → PE(18:2(9Z,12Z)/22:0) + Carbon dioxidedetails
PS(18:2(9Z,12Z)/22:1(13Z)) → PE(18:2(9Z,12Z)/22:1(13Z)) + Carbon dioxidedetails
PS(18:2(9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(18:2(9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
PS(18:3(6Z,9Z,12Z)/18:3(6Z,9Z,12Z)) → PE(18:3(6Z,9Z,12Z)/18:3(6Z,9Z,12Z)) + Carbon dioxidedetails
PS(18:3(6Z,9Z,12Z)/18:3(9Z,12Z,15Z)) → PE(18:3(6Z,9Z,12Z)/18:3(9Z,12Z,15Z)) + Carbon dioxidedetails
PS(18:3(6Z,9Z,12Z)/20:0) → PE(18:3(6Z,9Z,12Z)/20:0) + Carbon dioxidedetails
PS(18:3(6Z,9Z,12Z)/20:1(11Z)) → PE(18:3(6Z,9Z,12Z)/20:1(11Z)) + Carbon dioxidedetails
PS(18:3(6Z,9Z,12Z)/22:0) → PE(18:3(6Z,9Z,12Z)/22:0) + Carbon dioxidedetails
PS(18:3(6Z,9Z,12Z)/22:1(13Z)) → PE(18:3(6Z,9Z,12Z)/22:1(13Z)) + Carbon dioxidedetails
PS(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z)) → PE(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z)) + Carbon dioxidedetails
PS(18:3(9Z,12Z,15Z)/20:0) → PE(18:3(9Z,12Z,15Z)/20:0) + Carbon dioxidedetails
PS(18:3(9Z,12Z,15Z)/20:1(11Z)) → PE(18:3(9Z,12Z,15Z)/20:1(11Z)) + Carbon dioxidedetails
PS(18:3(9Z,12Z,15Z)/20:3(8Z,11Z,14Z)) → PE(18:3(9Z,12Z,15Z)/20:3(8Z,11Z,14Z)) + Carbon dioxidedetails
PS(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)) → PE(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxidedetails
PS(18:3(9Z,12Z,15Z)/22:0) → PE(18:3(9Z,12Z,15Z)/22:0) + Carbon dioxidedetails
PS(18:3(9Z,12Z,15Z)/22:1(13Z)) → PE(18:3(9Z,12Z,15Z)/22:1(13Z)) + Carbon dioxidedetails
PS(18:3(9Z,12Z,15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(18:3(9Z,12Z,15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
PS(20:0/20:0) → PE(20:0/20:0) + Carbon dioxidedetails
PS(20:0/20:1(11Z)) → PE(20:0/20:1(11Z)) + Carbon dioxidedetails
PS(20:0/22:0) → PE(20:0/22:0) + Carbon dioxidedetails
PS(20:0/22:1(13Z)) → PE(20:0/22:1(13Z)) + Carbon dioxidedetails
PS(20:1(11Z)/20:1(11Z)) → PE(20:1(11Z)/20:1(11Z)) + Carbon dioxidedetails
PS(20:1(11Z)/22:0) → PE(20:1(11Z)/22:0) + Carbon dioxidedetails
PS(20:1(11Z)/22:1(13Z)) → PE(20:1(11Z)/22:1(13Z)) + Carbon dioxidedetails
PS(20:3(8Z,11Z,14Z)/20:3(8Z,11Z,14Z)) → PE(20:3(8Z,11Z,14Z)/20:3(8Z,11Z,14Z)) + Carbon dioxidedetails
PS(20:3(8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) → PE(20:3(8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxidedetails
PS(20:3(8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(20:3(8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
PS(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) → PE(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxidedetails
PS(20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
PS(22:0/22:0) → PE(22:0/22:0) + Carbon dioxidedetails
PS(22:0/22:1(13Z)) → PE(22:0/22:1(13Z)) + Carbon dioxidedetails
PS(22:1(13Z)/22:1(13Z)) → PE(22:1(13Z)/22:1(13Z)) + Carbon dioxidedetails
PS(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxidedetails
General function:
Not Available
Specific function:
Not Available
Gene Name:
CPS1
Uniprot ID:
F1ML89
Molecular weight:
164740.0
Reactions
2 Adenosine triphosphate + Ammonia + Carbon dioxide + Water →2 ADP + Hydrogen phosphate + Carbamoylphosphatedetails
General function:
Not Available
Specific function:
Not Available
Gene Name:
DLD
Uniprot ID:
F1N206
Molecular weight:
54187.0
Reactions
Pyruvic acid + Coenzyme A + NAD → Acetyl-CoA + Carbon dioxide + NADHdetails
Oxoadipic acid + Coenzyme A → Glutaryl-CoA + Carbon dioxidedetails
General function:
Not Available
Specific function:
Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells. It is also a negative regulator of primary T-cells.
Gene Name:
NIT1
Uniprot ID:
Q32LH4
Molecular weight:
36240.0
Reactions
Ureidopropionic acid + Water → Beta-Alanine + Carbon dioxide + Ammoniadetails
Ureidopropionic acid + Water → Beta-Alanine + Ammonia + Carbon dioxidedetails
Ureidoisobutyric acid + Water → Ureidoisobutyric acid + Ammonia + Carbon dioxidedetails
Ureidoisobutyric acid + Water → 3-Aminoisobutanoic acid + Carbon dioxide + Ammoniadetails
General function:
Not Available
Specific function:
Not Available
Gene Name:
PPCDC
Uniprot ID:
Q58DB8
Molecular weight:
25180.0
Reactions
4-Phosphopantothenoylcysteine → Pantetheine 4'-phosphate + Carbon dioxidedetails
General function:
Not Available
Specific function:
Not Available
Gene Name:
PAICS
Uniprot ID:
Q2HJ26
Molecular weight:
47122.0
Reactions
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate → 5-Aminoimidazole ribonucleotide + Carbon dioxidedetails
General function:
Not Available
Specific function:
Not Available
Gene Name:
UROD
Uniprot ID:
E1BEX4
Molecular weight:
40812.0
Reactions
Uroporphyrinogen I → Coproporphyrinogen I +4 Carbon dioxidedetails
Uroporphyrinogen III → Coproporphyrinogen III +4 Carbon dioxidedetails
General function:
Not Available
Specific function:
Not Available
Gene Name:
CPOX
Uniprot ID:
E1BKY9
Molecular weight:
50380.0
Reactions
Coproporphyrinogen III + Oxygen + 2 Hydrogen → Protoporphyrinogen IX +2 Carbon dioxide +2 Waterdetails
General function:
Not Available
Specific function:
Not Available
Gene Name:
MLYCD
Uniprot ID:
A5PJC5
Molecular weight:
55416.0
Reactions
Malonyl-CoA → Acetyl-CoA + Carbon dioxidedetails