Showing metabocard for Carbon dioxide (BMDB0001967)
| Record Information | ||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Version | 1.0 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Creation Date | 2016-09-30 22:49:16 UTC | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Update Date | 2020-05-21 16:29:08 UTC | |||||||||||||||||||||||||||||||||||||||||||||||||||
| BMDB ID | BMDB0001967 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Secondary Accession Numbers |
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Metabolite Identification | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Common Name | Carbon dioxide | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Description | Carbon dioxide, also known as [CO2] or e 290, belongs to the class of inorganic compounds known as other non-metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of 'other non-metals'. Carbon dioxide is possibly neutral. Carbon dioxide exists in all living species, ranging from bacteria to humans. Carbon dioxide is a potentially toxic compound. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Structure |  | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Synonyms |
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Chemical Formula | CO2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Average Molecular Weight | 44.0095 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Monoisotopic Molecular Weight | 43.989829244 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| IUPAC Name | methanedione | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Traditional Name | carbon dioxide | |||||||||||||||||||||||||||||||||||||||||||||||||||
| CAS Registry Number | 124-38-9 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SMILES | O=C=O | |||||||||||||||||||||||||||||||||||||||||||||||||||
| InChI Identifier | InChI=1S/CO2/c2-1-3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| InChI Key | CURLTUGMZLYLDI-UHFFFAOYSA-N | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Chemical Taxonomy | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description | belongs to the class of inorganic compounds known as other non-metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of 'other non-metals'. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Kingdom | Inorganic compounds | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Super Class | Homogeneous non-metal compounds | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Class | Other non-metal organides | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Sub Class | Other non-metal oxides | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Direct Parent | Other non-metal oxides | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Alternative Parents | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Substituents |
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Framework | Not Available | |||||||||||||||||||||||||||||||||||||||||||||||||||
| External Descriptors |
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Ontology | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Status | Expected but not Quantified | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Origin |
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Biofunction | Not Available | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Application | Not Available | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Cellular locations |
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Physical Properties | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| State | Liquid | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Experimental Properties |
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Predicted Properties |
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Spectra | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Spectra | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Biological Properties | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cellular Locations |
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Biospecimen Locations |
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Pathways |
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Normal Concentrations | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abnormal Concentrations | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| External Links | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| HMDB ID | HMDB0001967 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| DrugBank ID | DB09157 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Phenol Explorer Compound ID | Not Available | |||||||||||||||||||||||||||||||||||||||||||||||||||
| FooDB ID | FDB014084 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| KNApSAcK ID | Not Available | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Chemspider ID | 274 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| KEGG Compound ID | C00011 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| BioCyc ID | CARBON-DIOXIDE | |||||||||||||||||||||||||||||||||||||||||||||||||||
| BiGG ID | 33506 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Wikipedia Link | Carbon_dioxide | |||||||||||||||||||||||||||||||||||||||||||||||||||
| METLIN ID | 3199 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PubChem Compound | 280 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PDB ID | Not Available | |||||||||||||||||||||||||||||||||||||||||||||||||||
| ChEBI ID | 16526 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| References | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Synthesis Reference | Callahan, Richard A. Process and apparatus for producing liquid carbon dioxide. U.S. (1993), Patent US5233837 (https://patents.google.com/patent/US5233837) | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Material Safety Data Sheet (MSDS) | Not Available | |||||||||||||||||||||||||||||||||||||||||||||||||||
| General References | Not Available | |||||||||||||||||||||||||||||||||||||||||||||||||||
Enzymes
- General function:
- Coenzyme transport and metabolism
- Specific function:
- Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference (By similarity). Required for adipocyte cell viability and metabolic homeostasis (By similarity).
- Gene Name:
- SPTLC1
- Uniprot ID:
- Q3MHG1
- Molecular weight:
- 52788.0
Reactions
| Palmityl-CoA + L-Serine → 3-Dehydrosphinganine + Carbon dioxide | details |
- General function:
- Lipid transport and metabolism
- Specific function:
- Performs the first committed step in the biosynthesis of isoprenes.
- Gene Name:
- MVD
- Uniprot ID:
- Q0P570
- Molecular weight:
- 43732.0
Reactions
| Adenosine triphosphate + 5-Diphosphomevalonic acid → ADP + Hydrogen phosphate + Isopentenyl pyrophosphate + Carbon dioxide | details |
- General function:
- Lipid transport and metabolism
- Specific function:
- Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor (By similarity).
- Gene Name:
- GCDH
- Uniprot ID:
- Q2KHZ9
- Molecular weight:
- 48472.0
Reactions
| Glutaryl-CoA → Crotonoyl-CoA + Carbon dioxide | details |
| Glutaryl-CoA + electron-transfer flavoprotein → Crotonoyl-CoA + Reduced electron-transfer flavoprotein + Carbon dioxide | details |
- General function:
- Involved in adenosylmethionine decarboxylase activity
- Specific function:
- Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
- Gene Name:
- AMD1
- Uniprot ID:
- P50243
- Molecular weight:
- 38365.0
Reactions
| S-Adenosylmethionine → S-Adenosylmethioninamine + Carbon dioxide | details |
- General function:
- Energy production and conversion
- Specific function:
- May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency.
- Gene Name:
- IDH1
- Uniprot ID:
- Q9XSG3
- Molecular weight:
- 46785.0
Reactions
| Isocitric acid + NADP → Oxoglutaric acid + NADPH + Carbon dioxide | details |
- General function:
- Energy production and conversion
- Specific function:
- Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal. May have a broader specificity and oxidize other aldehydes in vivo.
- Gene Name:
- ALDH1A1
- Uniprot ID:
- P48644
- Molecular weight:
- 54806.0
Reactions
| N10-Formyl-THF + NADP + Water → Tetrahydrofolic acid + Carbon dioxide + NADPH | details |
- General function:
- Energy production and conversion
- Specific function:
- Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate.
- Gene Name:
- PCK1
- Uniprot ID:
- Q8HYZ4
- Molecular weight:
- 69353.0
Reactions
| Guanosine triphosphate + Oxalacetic acid → Guanosine diphosphate + Phosphoenolpyruvic acid + Carbon dioxide | details |
- General function:
- Secondary metabolites biosynthesis, transport and catabolism
- Specific function:
- Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).
- Gene Name:
- TMLHE
- Uniprot ID:
- Q0VC74
- Molecular weight:
- 49837.0
Reactions
| N6,N6,N6-Trimethyl-L-lysine + Oxoglutaric acid + Oxygen → 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine + Succinic acid + Carbon dioxide | details |
| 3-Dehydroxycarnitine + Oxoglutaric acid + Oxygen → L-Carnitine + Succinic acid + Carbon dioxide | details |
- General function:
- Energy production and conversion
- Specific function:
- Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex (By similarity). The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (By similarity). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (By similarity).
- Gene Name:
- DLST
- Uniprot ID:
- P11179
- Molecular weight:
- 48973.0
Reactions
| Oxoadipic acid + Coenzyme A → Glutaryl-CoA + Carbon dioxide | details |
- General function:
- Coenzyme transport and metabolism
- Specific function:
- Involved in the catabolism of quinolinic acid (QA).
- Gene Name:
- QPRT
- Uniprot ID:
- Q3T063
- Molecular weight:
- 31151.0
Reactions
| Nicotinic acid mononucleotide + Pyrophosphate + Carbon dioxide → Quinolinic acid + Phosphoribosyl pyrophosphate | details |
- General function:
- Energy production and conversion
- Specific function:
- The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
- Gene Name:
- BCKDHA
- Uniprot ID:
- P11178
- Molecular weight:
- 51678.0
Reactions
| Ketoleucine + Thiamine pyrophosphate → 3-Methyl-1-hydroxybutyl-ThPP + Carbon dioxide | details |
| Alpha-ketoisovaleric acid + Thiamine pyrophosphate → 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide | details |
| 3-Methyl-2-oxovaleric acid + Thiamine pyrophosphate → 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide | details |
- General function:
- Energy production and conversion
- Specific function:
- The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
- Gene Name:
- BCKDHB
- Uniprot ID:
- P21839
- Molecular weight:
- 42935.0
Reactions
| Ketoleucine + Thiamine pyrophosphate → 3-Methyl-1-hydroxybutyl-ThPP + Carbon dioxide | details |
| Alpha-ketoisovaleric acid + Thiamine pyrophosphate → 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide | details |
| 3-Methyl-2-oxovaleric acid + Thiamine pyrophosphate → 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide | details |
- General function:
- Involved in aminocarboxymuconate-semialdehyde decarboxy
- Specific function:
- Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway (By similarity).
- Gene Name:
- ACMSD
- Uniprot ID:
- Q0II68
- Molecular weight:
- 37923.0
Reactions
| 2-Amino-3-carboxymuconic acid semialdehyde → 2-Aminomuconic acid semialdehyde + Carbon dioxide | details |
- General function:
- Involved in iron ion binding
- Specific function:
- Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
- Gene Name:
- P4HA3
- Uniprot ID:
- Q75UG4
- Molecular weight:
- 61023.0
Reactions
| L-Proline + Oxoglutaric acid + Oxygen → Hydroxyproline + Succinic acid + Carbon dioxide | details |
- General function:
- Energy production and conversion
- Specific function:
- Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.
- Gene Name:
- PDHX
- Uniprot ID:
- P22439
- Molecular weight:
- 53886.0
Reactions
| Pyruvic acid + Coenzyme A + NAD → Acetyl-CoA + Carbon dioxide + NADH | details |
- General function:
- Amino acid transport and metabolism
- Specific function:
- Catalyzes the production of GABA.
- Gene Name:
- GAD1
- Uniprot ID:
- Q0VCA1
- Molecular weight:
- 66784.0
Reactions
| L-Aspartic acid → Beta-Alanine + Carbon dioxide | details |
| L-Glutamic acid → Gamma-Aminobutyric acid + Carbon dioxide | details |
| 3-Sulfinoalanine → Hypotaurine + Carbon dioxide | details |
| Cysteic acid → Taurine + Carbon dioxide | details |
- General function:
- Amino acid transport and metabolism
- Specific function:
- Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
- Gene Name:
- ODC1
- Uniprot ID:
- P27117
- Molecular weight:
- 51346.0
Reactions
| Ornithine → Putrescine + Carbon dioxide | details |
- General function:
- Amino acid transport and metabolism
- Specific function:
- Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
- Gene Name:
- DDC
- Uniprot ID:
- P27718
- Molecular weight:
- 54294.0
Reactions
| L-Tyrosine → Tyramine + Carbon dioxide | details |
| 5-Hydroxykynurenine → 5-Hydroxykynurenamine + Carbon dioxide | details |
| L-Tryptophan → Tryptamine + Carbon dioxide | details |
- General function:
- Cell wall/membrane/envelope biogenesis
- Specific function:
- Involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis.
- Gene Name:
- NSDHL
- Uniprot ID:
- Q3ZBE9
- Molecular weight:
- 39902.0
Reactions
| 4a-Methylzymosterol-4-carboxylic acid + NADP → 3-Keto-4-methylzymosterol + NADPH + Carbon dioxide | details |
- General function:
- Energy production and conversion
- Specific function:
- 2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.
- Gene Name:
- OGDH
- Uniprot ID:
- Q148N0
- Molecular weight:
- 115808.0
Reactions
| Oxoadipic acid + Coenzyme A → Glutaryl-CoA + Carbon dioxide | details |
- General function:
- Energy production and conversion
- Specific function:
- The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
- Gene Name:
- PDHA1
- Uniprot ID:
- A7MB35
- Molecular weight:
- 43388.0
Reactions
| Pyruvic acid + Coenzyme A + NAD → Acetyl-CoA + Carbon dioxide + NADH | details |
| Pyruvic acid + Lipoamide → S-Acetyldihydrolipoamide-E + Carbon dioxide | details |
- General function:
- Energy production and conversion
- Specific function:
- The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
- Gene Name:
- PDHB
- Uniprot ID:
- P11966
- Molecular weight:
- 39126.0
Reactions
| Pyruvic acid + Coenzyme A + NAD → Acetyl-CoA + Carbon dioxide + NADH | details |
| Pyruvic acid + Lipoamide → S-Acetyldihydrolipoamide-E + Carbon dioxide | details |
- General function:
- Amino acid transport and metabolism
- Specific function:
- Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is L-aspartate. Does not exhibit any decarboxylation activity toward glutamate.
- Gene Name:
- GADL1
- Uniprot ID:
- A6QM00
- Molecular weight:
- 59380.0
Reactions
| 3-Sulfinoalanine → Hypotaurine + Carbon dioxide | details |
| Cysteic acid → Taurine + Carbon dioxide | details |
- General function:
- Not Available
- Specific function:
- Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
- Gene Name:
- PISD
- Uniprot ID:
- Q58DH2
- Molecular weight:
- 47244.0
Reactions
| an L-1-Phosphatidylserine → Carbon dioxide + an L-1-Phosphatidylethanolamine | details |
| PS(14:0/14:0) → PE(14:0/14:0) + Carbon dioxide | details |
| PS(14:0/14:1(9Z)) → PE(14:0/14:1(9Z)) + Carbon dioxide | details |
| PS(14:0/16:0) → PE(14:0/16:0) + Carbon dioxide | details |
| PS(14:0/16:1(9Z)) → PE(14:0/16:1(9Z)) + Carbon dioxide | details |
| PS(14:0/18:0) → PE(14:0/18:0) + Carbon dioxide | details |
| PS(14:0/18:1(9Z)) → PE(14:0/18:1(9Z)) + Carbon dioxide | details |
| PS(14:0/18:2(9Z,12Z)) → PE(14:0/18:2(9Z,12Z)) + Carbon dioxide | details |
| PS(14:0/18:3(9Z,12Z,15Z)) → PE(14:0/18:3(9Z,12Z,15Z)) + Carbon dioxide | details |
| PS(14:0/20:3(8Z,11Z,14Z)) → PE(14:0/20:3(8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(14:0/20:4(5Z,8Z,11Z,14Z)) → PE(14:0/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
| PS(14:1(9Z)/14:1(9Z)) → PE(14:1(9Z)/14:1(9Z)) + Carbon dioxide | details |
| PS(14:1(9Z)/16:0) → PE(14:1(9Z)/16:0) + Carbon dioxide | details |
| PS(14:1(9Z)/16:1(9Z)) → PE(14:1(9Z)/16:1(9Z)) + Carbon dioxide | details |
| PS(14:1(9Z)/18:0) → PE(14:1(9Z)/18:0) + Carbon dioxide | details |
| PS(14:1(9Z)/18:1(9Z)) → PE(14:1(9Z)/18:1(9Z)) + Carbon dioxide | details |
| PS(14:1(9Z)/18:2(9Z,12Z)) → PE(14:1(9Z)/18:2(9Z,12Z)) + Carbon dioxide | details |
| PS(14:1(9Z)/18:3(9Z,12Z,15Z)) → PE(14:1(9Z)/18:3(9Z,12Z,15Z)) + Carbon dioxide | details |
| PS(14:1(9Z)/20:3(8Z,11Z,14Z)) → PE(14:1(9Z)/20:3(8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(14:1(9Z)/20:4(5Z,8Z,11Z,14Z)) → PE(14:1(9Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(14:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(14:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
| PS(16:0/16:1(9Z)) → PE(16:0/16:1(9Z)) + Carbon dioxide | details |
| PS(16:0/18:0) → PE(16:0/18:0) + Carbon dioxide | details |
| PS(16:0/18:1(11Z)) → PE(16:0/18:1(11Z)) + Carbon dioxide | details |
| PS(16:0/18:1(9Z)) → PE(16:0/18:1(9Z)) + Carbon dioxide | details |
| PS(16:0/18:2(9Z,12Z)) → PE(16:0/18:2(9Z,12Z)) + Carbon dioxide | details |
| PS(16:0/18:3(6Z,9Z,12Z)) → PE(16:0/18:3(6Z,9Z,12Z)) + Carbon dioxide | details |
| PS(16:0/18:3(9Z,12Z,15Z)) → PE(16:0/18:3(9Z,12Z,15Z)) + Carbon dioxide | details |
| PS(16:0/20:0) → PE(16:0/20:0) + Carbon dioxide | details |
| PS(16:0/20:1(11Z)) → PE(16:0/20:1(11Z)) + Carbon dioxide | details |
| PS(16:0/20:3(8Z,11Z,14Z)) → PE(16:0/20:3(8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(16:0/20:4(5Z,8Z,11Z,14Z)) → PE(16:0/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(16:0/22:0) → PE(16:0/22:0) + Carbon dioxide | details |
| PS(16:0/22:1(13Z)) → PE(16:0/22:1(13Z)) + Carbon dioxide | details |
| PS(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
| PS(16:1(9Z)/16:1(9Z)) → PE(16:1(9Z)/16:1(9Z)) + Carbon dioxide | details |
| PS(16:1(9Z)/18:0) → PE(16:1(9Z)/18:0) + Carbon dioxide | details |
| PS(16:1(9Z)/18:1(9Z)) → PE(16:1(9Z)/18:1(9Z)) + Carbon dioxide | details |
| PS(16:1(9Z)/18:2(9Z,12Z)) → PE(16:1(9Z)/18:2(9Z,12Z)) + Carbon dioxide | details |
| PS(16:1(9Z)/18:3(9Z,12Z,15Z)) → PE(16:1(9Z)/18:3(9Z,12Z,15Z)) + Carbon dioxide | details |
| PS(16:1(9Z)/20:3(8Z,11Z,14Z)) → PE(16:1(9Z)/20:3(8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(16:1(9Z)/20:4(5Z,8Z,11Z,14Z)) → PE(16:1(9Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
| PS(18:0/18:0) → PE(18:0/18:0) + Carbon dioxide | details |
| PS(18:0/18:1(11Z)) → PE(18:0/18:1(11Z)) + Carbon dioxide | details |
| PS(18:0/18:1(9Z)) → PE(18:0/18:1(9Z)) + Carbon dioxide | details |
| PS(18:0/18:2(9Z,12Z)) → PE(18:0/18:2(9Z,12Z)) + Carbon dioxide | details |
| PS(18:0/18:3(6Z,9Z,12Z)) → PE(18:0/18:3(6Z,9Z,12Z)) + Carbon dioxide | details |
| PS(18:0/18:3(9Z,12Z,15Z)) → PE(18:0/18:3(9Z,12Z,15Z)) + Carbon dioxide | details |
| PS(18:0/20:0) → PE(18:0/20:0) + Carbon dioxide | details |
| PS(18:0/20:1(11Z)) → PE(18:0/20:1(11Z)) + Carbon dioxide | details |
| PS(18:0/20:3(8Z,11Z,14Z)) → PE(18:0/20:3(8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(18:0/20:4(5Z,8Z,11Z,14Z)) → PE(18:0/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(18:0/20:4(8Z,11Z,14Z,17Z)) → PE(18:0/20:4(8Z,11Z,14Z,17Z)) + Carbon dioxide | details |
| PS(18:0/22:0) → PE(18:0/22:0) + Carbon dioxide | details |
| PS(18:0/22:1(13Z)) → PE(18:0/22:1(13Z)) + Carbon dioxide | details |
| PS(18:0/22:5(7Z,10Z,13Z,16Z,19Z)) → PE(18:0/22:5(7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
| PS(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
| PS(18:1(11Z)/18:1(11Z)) → PE(18:1(11Z)/18:1(11Z)) + Carbon dioxide | details |
| PS(18:1(11Z)/18:2(9Z,12Z)) → PE(18:1(11Z)/18:2(9Z,12Z)) + Carbon dioxide | details |
| PS(18:1(11Z)/18:3(6Z,9Z,12Z)) → PE(18:1(11Z)/18:3(6Z,9Z,12Z)) + Carbon dioxide | details |
| PS(18:1(11Z)/18:3(9Z,12Z,15Z)) → PE(18:1(11Z)/18:3(9Z,12Z,15Z)) + Carbon dioxide | details |
| PS(18:1(11Z)/20:0) → PE(18:1(11Z)/20:0) + Carbon dioxide | details |
| PS(18:1(11Z)/20:1(11Z)) → PE(18:1(11Z)/20:1(11Z)) + Carbon dioxide | details |
| PS(18:1(11Z)/22:0) → PE(18:1(11Z)/22:0) + Carbon dioxide | details |
| PS(18:1(11Z)/22:1(13Z)) → PE(18:1(11Z)/22:1(13Z)) + Carbon dioxide | details |
| PS(18:1(9Z)/18:1(9Z)) → PE(18:1(9Z)/18:1(9Z)) + Carbon dioxide | details |
| PS(18:1(9Z)/18:2(9Z,12Z)) → PE(18:1(9Z)/18:2(9Z,12Z)) + Carbon dioxide | details |
| PS(18:1(9Z)/18:3(6Z,9Z,12Z)) → PE(18:1(9Z)/18:3(6Z,9Z,12Z)) + Carbon dioxide | details |
| PS(18:1(9Z)/18:3(9Z,12Z,15Z)) → PE(18:1(9Z)/18:3(9Z,12Z,15Z)) + Carbon dioxide | details |
| PS(18:1(9Z)/20:0) → PE(18:1(9Z)/20:0) + Carbon dioxide | details |
| PS(18:1(9Z)/20:1(11Z)) → PE(18:1(9Z)/20:1(11Z)) + Carbon dioxide | details |
| PS(18:1(9Z)/20:3(8Z,11Z,14Z)) → PE(18:1(9Z)/20:3(8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(18:1(9Z)/20:4(5Z,8Z,11Z,14Z)) → PE(18:1(9Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(18:1(9Z)/22:0) → PE(18:1(9Z)/22:0) + Carbon dioxide | details |
| PS(18:1(9Z)/22:1(13Z)) → PE(18:1(9Z)/22:1(13Z)) + Carbon dioxide | details |
| PS(18:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(18:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
| PS(18:2(9Z,12Z)/18:2(9Z,12Z)) → PE(18:2(9Z,12Z)/18:2(9Z,12Z)) + Carbon dioxide | details |
| PS(18:2(9Z,12Z)/18:3(6Z,9Z,12Z)) → PE(18:2(9Z,12Z)/18:3(6Z,9Z,12Z)) + Carbon dioxide | details |
| PS(18:2(9Z,12Z)/18:3(9Z,12Z,15Z)) → PE(18:2(9Z,12Z)/18:3(9Z,12Z,15Z)) + Carbon dioxide | details |
| PS(18:2(9Z,12Z)/20:0) → PE(18:2(9Z,12Z)/20:0) + Carbon dioxide | details |
| PS(18:2(9Z,12Z)/20:1(11Z)) → PE(18:2(9Z,12Z)/20:1(11Z)) + Carbon dioxide | details |
| PS(18:2(9Z,12Z)/20:3(8Z,11Z,14Z)) → PE(18:2(9Z,12Z)/20:3(8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z)) → PE(18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(18:2(9Z,12Z)/22:0) → PE(18:2(9Z,12Z)/22:0) + Carbon dioxide | details |
| PS(18:2(9Z,12Z)/22:1(13Z)) → PE(18:2(9Z,12Z)/22:1(13Z)) + Carbon dioxide | details |
| PS(18:2(9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(18:2(9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
| PS(18:3(6Z,9Z,12Z)/18:3(6Z,9Z,12Z)) → PE(18:3(6Z,9Z,12Z)/18:3(6Z,9Z,12Z)) + Carbon dioxide | details |
| PS(18:3(6Z,9Z,12Z)/18:3(9Z,12Z,15Z)) → PE(18:3(6Z,9Z,12Z)/18:3(9Z,12Z,15Z)) + Carbon dioxide | details |
| PS(18:3(6Z,9Z,12Z)/20:0) → PE(18:3(6Z,9Z,12Z)/20:0) + Carbon dioxide | details |
| PS(18:3(6Z,9Z,12Z)/20:1(11Z)) → PE(18:3(6Z,9Z,12Z)/20:1(11Z)) + Carbon dioxide | details |
| PS(18:3(6Z,9Z,12Z)/22:0) → PE(18:3(6Z,9Z,12Z)/22:0) + Carbon dioxide | details |
| PS(18:3(6Z,9Z,12Z)/22:1(13Z)) → PE(18:3(6Z,9Z,12Z)/22:1(13Z)) + Carbon dioxide | details |
| PS(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z)) → PE(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z)) + Carbon dioxide | details |
| PS(18:3(9Z,12Z,15Z)/20:0) → PE(18:3(9Z,12Z,15Z)/20:0) + Carbon dioxide | details |
| PS(18:3(9Z,12Z,15Z)/20:1(11Z)) → PE(18:3(9Z,12Z,15Z)/20:1(11Z)) + Carbon dioxide | details |
| PS(18:3(9Z,12Z,15Z)/20:3(8Z,11Z,14Z)) → PE(18:3(9Z,12Z,15Z)/20:3(8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)) → PE(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(18:3(9Z,12Z,15Z)/22:0) → PE(18:3(9Z,12Z,15Z)/22:0) + Carbon dioxide | details |
| PS(18:3(9Z,12Z,15Z)/22:1(13Z)) → PE(18:3(9Z,12Z,15Z)/22:1(13Z)) + Carbon dioxide | details |
| PS(18:3(9Z,12Z,15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(18:3(9Z,12Z,15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
| PS(20:0/20:0) → PE(20:0/20:0) + Carbon dioxide | details |
| PS(20:0/20:1(11Z)) → PE(20:0/20:1(11Z)) + Carbon dioxide | details |
| PS(20:0/22:0) → PE(20:0/22:0) + Carbon dioxide | details |
| PS(20:0/22:1(13Z)) → PE(20:0/22:1(13Z)) + Carbon dioxide | details |
| PS(20:1(11Z)/20:1(11Z)) → PE(20:1(11Z)/20:1(11Z)) + Carbon dioxide | details |
| PS(20:1(11Z)/22:0) → PE(20:1(11Z)/22:0) + Carbon dioxide | details |
| PS(20:1(11Z)/22:1(13Z)) → PE(20:1(11Z)/22:1(13Z)) + Carbon dioxide | details |
| PS(20:3(8Z,11Z,14Z)/20:3(8Z,11Z,14Z)) → PE(20:3(8Z,11Z,14Z)/20:3(8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(20:3(8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) → PE(20:3(8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(20:3(8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(20:3(8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
| PS(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) → PE(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) + Carbon dioxide | details |
| PS(20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
| PS(22:0/22:0) → PE(22:0/22:0) + Carbon dioxide | details |
| PS(22:0/22:1(13Z)) → PE(22:0/22:1(13Z)) + Carbon dioxide | details |
| PS(22:1(13Z)/22:1(13Z)) → PE(22:1(13Z)/22:1(13Z)) + Carbon dioxide | details |
| PS(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) → PE(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Carbon dioxide | details |
- General function:
- Not Available
- Specific function:
- Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells. It is also a negative regulator of primary T-cells.
- Gene Name:
- NIT1
- Uniprot ID:
- Q32LH4
- Molecular weight:
- 36240.0
Reactions
| Ureidopropionic acid + Water → Beta-Alanine + Carbon dioxide + Ammonia | details |
| Ureidopropionic acid + Water → Beta-Alanine + Ammonia + Carbon dioxide | details |
| Ureidoisobutyric acid + Water → Ureidoisobutyric acid + Ammonia + Carbon dioxide | details |
| Ureidoisobutyric acid + Water → 3-Aminoisobutanoic acid + Carbon dioxide + Ammonia | details |